Acts 13:51 But they shook off the dust from their feet against them, and came to Iconium.
Do you know how hard it is to turn your back on someone when you know you are trying to tell them the truth?
I know it is very hard, but don’t look at it as turning your back on them. They are still there and you can still think about them and pray for them; just don’t waste too much energy trying to teach them the gospel.
There are plenty of people who God has prepared for us to talk to and plenty He knows will reject Him.
Follow God’s instructions and continue to talk to people who are willing to listen. He will work with the ones who are not and will change their hearts when He wants to.