2 Timothy 4:22 The Lord Jesus Christ be with your spirit. Grace be with you. Amen.
Have you ever wondered why this should talk about the Lord being with our spirit?
When Christ changes us, He changes our spirit. Our souls are us, the part of us that defines us through our minds, emotions and will.
God changes the part of us that defines our relationship with Him; if we have God with our spirits, we are a new being because God cannot accept sin.
This does not mean we stop sinning because we still sin through our souls even if the spirit has been changed.